Ozempic, other semaglutides linked to hair loss: Here's what to know

Semaglutide medications similar Ozempic and Wegovy person exploded successful popularity successful caller years owed to their effectiveness successful diabetes power and value loss. 

Research has revealed further benefits beyond those superior uses — but immoderate antagonistic broadside effects person besides emerged.

While gastrointestinal issues are the astir communal broadside effects, a caller survey by the University of British Columbia linked GLP-1 (glucagon-like peptide-1) agonists — the people of drugs that includes semaglutides — to an accrued hazard of hairsbreadth loss.

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The researchers analyzed information from 16 cardinal patients from a wellness claims database, narrowing it down to 1,926 semaglutide users and 1,348 users of bupropion-naltrexone, different benignant of weight-loss medication.

A caller survey by the University of British Columbia linked GLP-1 (glucagon-like peptide-1) agonists — the people of drugs that includes semaglutides — to an accrued hazard of hairsbreadth loss. (iStock)

After adjusting for different factors, they recovered that the semaglutide users were wide 50% much apt to acquisition hairsbreadth nonaccomplishment compared to the different group.

Women were much apt to person this outcome, with doubly the hazard of men.

‘Not surprising’

The researchers were not amazed by the results, according to co-study writer Dr. Mahyar Etminan, an epidemiologist and CEO of Epilytics successful Vancouver, British Columbia, Canada.

"There were [previous] anecdotal reports of hairsbreadth nonaccomplishment and besides reports of hairsbreadth nonaccomplishment successful objective trials of the drugs," helium told Fox News Digital.

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Dr. Patrick Davis, a Beverly Hills integrative surgeon and hairsbreadth restoration expert, agreed that the findings were not surprising.

"We person heard this anecdotally erstwhile patients consult america for surgical restoration of their look aft accelerated value loss," helium said successful an interrogation with Fox News Digital.

After adjusting for different factors, researchers recovered that the semaglutide users were wide 50% much apt to acquisition hairsbreadth nonaccomplishment compared to the different group. (iStock)

"Hair maturation (and loss) are rather babelike connected factors specified arsenic diet, indispensable vitamins, bodily accent and genetics."

The archetypal 3 factors travel into play during value loss, helium noted — "and semaglutide-driven nonaccomplishment is apt nary exception."

Previous studies person shown that changes inducing accent oregon affecting one’s nutritional intake could airs an accrued hazard of hairsbreadth loss, the doc added. 

"Hair maturation (and loss) are rather babelike connected factors specified arsenic diet, indispensable vitamins, bodily accent and genetics."

"This survey references that those who mislaid much than 20% of their assemblage value had higher rates of hairsbreadth nonaccomplishment than those who didn’t," Davis noted. 

"This survey theorizes that this whitethorn beryllium owed to suspected physiological stress, which whitethorn beryllium a grounds of specified accelerated value loss."

Long-term hairsbreadth nonaccomplishment seems to beryllium much unlikely, the doc said, arsenic the "inciting event" (weight nonaccomplishment and stress) often normalizes arsenic individuals scope their people weight.

Potential limitations

The survey did person immoderate limitations, noted researcher Etminan.

Those included the information that it could not verify hairsbreadth nonaccomplishment done aesculapian records, but lone identified aesculapian codes for hairsbreadth loss.

Women were much apt to acquisition semaglutide-related hairsbreadth loss, with doubly the hazard of men. (iStock)

Davis, the integrative surgeon, besides noted that this probe references different survey successful which Wegovy users had an elevated hazard of hairsbreadth nonaccomplishment (3.3%) comparative to the placebo radical (1.4%). 

"While this intelligibly shows an accrued risk, 3.3% is inactive a precise debased complaint of incidence," helium said.

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This aboriginal study, which was published successful the preprint server medRxiv, has not yet been peer-reviewed.

"Future studies are required to ascertain the relation betwixt semaglutide and hairsbreadth loss," the researchers wrote.

Doctors' advice

Those who acquisition hairsbreadth nonaccomplishment portion taking semaglutide drugs should consult with a dermatologist to find whether it's owed to an adverse effect of these medications, Etminan advised.

"This is simply a comparatively caller adverse lawsuit and not overmuch is known astir it," helium said. "Questions astir who is astir astatine hazard and whether the hairsbreadth nonaccomplishment volition reverse upon stopping the cause tin beryllium addressed successful aboriginal studies."

When contacted by Fox News Digital, Novo Nordisk — shaper of Ozempic and Wegovy — confirmed that hairsbreadth nonaccomplishment is an identified hazard for semaglutide, and is listed arsenic a broadside effect successful the merchandise information. (Getty Images)

Davis agreed, encouraging patients to person an unfastened speech with their doc astir however they tin champion instrumentality attraction of themselves. 

"I judge a diligent should instrumentality immoderate imaginable broadside effects into information earlier taking immoderate medication," helium said. 

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"While the complaint of incidence of hairsbreadth nonaccomplishment is inactive decidedly low, it’s a imaginable trade-off that a diligent should consider." 

Davis besides recommends that his patients follow a "hearty diet" consisting of fiber, macromolecule and nutritious foods to guarantee due nourishment portion taking a semaglutide medication.

Those who acquisition hairsbreadth nonaccomplishment portion taking semaglutide drugs should consult with a dermatologist to find whether it's owed to an adverse effect of these medications, an adept advised. (iStock)

"Not lone whitethorn this assistance with hairsbreadth loss, but much importantly, a beardown fare tin curb the unwanted nonaccomplishment of musculus wide that often occurs," helium said. "A due diet, blimpish timetable for value loss, and program for workout are indispensable erstwhile taking this medication."

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When contacted by Fox News Digital, Novo Nordisk — shaper of Ozempic and Wegovy — confirmed that hairsbreadth nonaccomplishment is an identified hazard for semaglutide, and is listed arsenic a broadside effect successful the merchandise information.

"In objective trials of Wegovy, hairsbreadth nonaccomplishment was reported successful 2.5% of Wegovy-treated big patients versus 1.0% of placebo-treated big patients," the institution spokesperson said. 

"While the complaint of incidence of hairsbreadth nonaccomplishment is inactive decidedly low, it’s a imaginable trade-off that a diligent should consider."

"Hair nonaccomplishment was reported much often successful patients with greater value nonaccomplishment (≥20%), suggesting that the events of hairsbreadth nonaccomplishment were perchance related to the magnitude of value loss."

"Patient information is of utmost value to Novo Nordisk," the connection continued. "We are continuously monitoring the information illustration of our products and collaborate intimately with authorities to guarantee diligent safety, including capable accusation connected hairsbreadth loss."

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The survey was funded by interior probe funds from the Department of Ophthalmology and Visual Sciences, University of British Columbia, the diary nonfiction stated.